Predict how blood and urine pH may be affected in a patient with continued decline in kidney function due to damage and/or partial nephrectomy and increased production of acidic metabolites (i.e., ketones). Be sure to discuss compensatory mechanisms for long-term acid-base balance, including a detailed discussion of the kidney’s role in H+ and HCO- transport. Predict blood and urine pH (low/high) with increased ketones and decreased glomerular filtration rate.
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