Question 1 [10 marks) When we culture microorganisms in lab scale, eg. using a shake flask, we get results with high efficiency. However, when such microbial cultures are aimed for scaling up for an industrial application using bioreactor (may be in diverse fields) we face a lot of problems’. Imagine you are one of the design engineers in your company, you are required to solve these issues. a) Analyse issues related to scaling up the microbial cultures b) List the solutions for each issue in (a) [5 marks) [5 marks)

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